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Braz. j. microbiol ; 46(2): 613-617, Apr-Jun/2015. tab, graf
Article in English | LILACS | ID: lil-749716

ABSTRACT

In this study, we revealed that OA and UA significantly inhibited the expression of most genes related to peptidoglycan biosynthesis in S. mutans UA159. To the best of our knowledge, this is the first report to introduce the antimicrobial mechanism of OA and UA against S. mutans.


Subject(s)
Anti-Bacterial Agents/pharmacology , Biosynthetic Pathways/drug effects , Biosynthetic Pathways/genetics , Oleanolic Acid/pharmacology , Peptidoglycan/biosynthesis , Streptococcus mutans/drug effects , Triterpenes/pharmacology , Gene Expression Regulation, Bacterial/drug effects
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